Excellent guide, Sander, it works really well. In fact I just tried it, and it resulted in the following totally stupid situtation:
I decided to use a 1000-star galaxy, and since I put 6 AI on it, instead of the one in your guide, I thought, "eh, better put them on medium just to be safe."
So about 30 minutes in with over 3M metal, I sent out a colony swarm and a batch of the final 500 probe droids. 20 minutes later, I finally finished getting all of the new colonies set up, and zoomed out to check on the AI now that I could see all of the systems... Me: ~200 systems. AI... 5 each?! No wonder even the aggro ones accepted my peace offers in about 5 nanoseconds.
I guess hard/cheat is the min AI you should use with this.
Also, several of the ship designs have all of the components stacked on top of each other. They work so long as you don't touch them, but they're impossible to see what's going on or tweak.